Endocrine Abstracts

Introduction: Hyperfunctioning thyroid nodules (toxic adenomas) comprise one of the most common causes of hyperthyroidism and are usually treated with therapeutic radioiodine administration (RAI). Coexistence of such nodules with Graves’ disease (GD) is a rare disorder (Marine-Lenhart syndrome) with a reported prevalence of approximately 2.7–4.1% in GD patients. We present a rare variant of this condition, featuring the case of a patient with hyperfunctioning nodul...

IntroductionThyroid autoimmunity comprises a dynamic entity and may manifest with different forms over the course of time at the same patient, thus causing fluctuations in thyroid functionality. Hereby, we present the case of a patient treated for hypothyroidism of autoimmune etiology, who developed hyperthyroidism accompanied by an excess of thyrotropin receptor autoantibodies (TRAb) and was followed by multiple swings in the thyroid state over an 1.5-y...

Introduction: Primary hyperparathyroidism comprises one of the major causes of hypercalcaemia and is mostly due to solitary parathyroid adenoma. Denosumab is a novel antiresorptive agent for osteoporosis treatment and has been associated with a compensatory increase in PTH levels during the first months after injection, a fact that may interfere in the diagnostic procedures when dealing with concomitant small parathyroid adenomas without standard scintigraphic pattern.<p c...